The Problem of Alzheimer's Spiral-Bound | 2022-11-01

Jason Karlawish

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A definitive and compelling book on one of today's most prevalent illnesses.

In 2020, an estimated 5.8 million Americans had Alzheimer's, and more than half a million died because of the disease and its devastating complications. 16 million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their seventies and eighties, the number of patients will rise to an estimated 13.8 million by 2025.

Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer's from its beginnings to its recognition as a crisis. While it is an unambiguous account of decades of missed opportunities and our health care systems' failures to take action, it tells the story of the biomedical breakthroughs that may allow Alzheimer's to finally be prevented and treated by medicine and also presents an argument for how we can live with dementia: the ways patients can reclaim their autonomy and redefine their sense of self, how families can support their loved ones, and the innovative reforms we can make as a society that would give caregivers and patients better quality of life.

Rich in science, history, and characters, The Problem of Alzheimer's takes us inside laboratories, patients' homes, caregivers' support groups, progressive care communities, and Jason Karlawish's own practice at the Penn Memory Center.

Publisher: Macmillan
Original Binding: Trade Paperback
Pages: 368 pages
ISBN-10: 1250861772
Item Weight: 0.9 lbs
Dimensions: 9.4 x 1.3 x 9.2 inches
"A meticulous and deeply researched inquiry into one of the most mysterious illnesses that affects humans." -- Siddhartha Mukherjee, New York Times bestselling author of The Emperor of All Maladies and The Gene

"A must-read on an important subject." --Library Journal (starred review)

"Karlawish presents tough information and hard questions with emotional tact. This is a real eye-opener." --
Publishers Weekly


JASON KARLAWISH is a physician and writer. He is the author of the novel Open Wound and his essays have appeared in The New York Times, The Washington Post, Forbes and the Philadelphia Inquirer. He is a Professor of Medicine, Medical Ethics and Health Policy, and Neurology at the University of Pennsylvania and Co-Director of the Penn Memory Center, where he cares for patients. He lives in Philadelphia.